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Taven EZ 10/10mg Tablet 1 Strip
- Taven EZ 10/10 is for the treatment of high cholesterol.
- Take it in addition to regular exercise and a low-fat diet to lower levels of fat in the blood.
- Taven EZ 10/10 can be taken with or without food.
- Notify your doctor if you experience muscle symptoms (pain or weakness), particularly if accompanied by fever.
- Notify your doctor if you experience stomach pain, loss of appetite, a sick feeling, or dark urine.
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✅ Description:
Taven EZ 10/10 is intended as part of a comprehensive treatment plan for patients at high risk of atherosclerotic cardiovascular disease due to elevated cholesterol levels. Medication should be used alongside dietary restrictions (low in saturated fat and cholesterol) and other non-drug interventions when such measures alone do not sufficiently reduce lipid levels.
Primary Hyperlipidemia: Taven EZ is indicated to reduce elevated levels of total cholesterol, LDL-C, triglycerides, Apo B, and non-HDL cholesterol, while increasing HDL-C in individuals with primary (familial or non-familial) or mixed hyperlipidemia.
Homozygous Familial Hypercholesterolemia (HoFH): It is also prescribed to lower total cholesterol and LDL-C in HoFH patients, either in combination with other lipid-lowering therapies (e.g., LDL apheresis) or when such treatments are not available.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Pharmacology of Taven EZ 10/10
Atorvastatin: This statin works by inhibiting HMG-CoA reductase, an enzyme involved in cholesterol synthesis in the liver. It helps reduce plasma cholesterol by promoting hepatic uptake and degradation of LDL through upregulation of LDL receptors.
Ezetimibe: This agent reduces cholesterol absorption in the small intestine by targeting the sterol transporter NPC1L1. This inhibition results in reduced cholesterol delivery to the liver, leading to lower hepatic cholesterol stores and increased clearance of circulating cholesterol. Its mechanism complements that of statins, without affecting the synthesis of cholesterol or bile acid excretion.
✔️ Side Effects of Taven EZ 10/10
- Muscle pain or weakness (myopathy, rhabdomyolysis)
- Elevated liver enzymes
- Abdominal discomfort
- General muscle aches
✔️ Dosage & Administration of Taven EZ 10/10
Typical dosage ranges from 10/10 mg to 80/20 mg once daily.
The initial dose is usually 10/10 mg or 20/10 mg once daily, with 40/10 mg recommended for those needing a significant LDL-C reduction (≥55%).
Dose adjustments should be based on lipid profile assessment done at least 2 weeks after starting or changing the dose.
- For HoFH Patients: A daily dose of 40/10 mg or 80/10 mg is advised, used with other lipid-lowering therapies if available.
- Hepatic impairment: Contraindicated in active liver disease or unexplained high transaminase levels.
- Renal impairment: While no dosage adjustment is needed, monitor patients closely for muscle-related side effects.
- Pediatric use: Not established.
- Geriatric use: No dose adjustment required.
Take only as prescribed by a registered medical professional
✔️ Drug Interaction
The likelihood of muscle damage (myopathy/rhabdomyolysis) increases when statins are used with:
- Fibrates (e.g., gemfibrozil) – avoid co-use.
- Niacin (in lipid-lowering doses) – use with caution.
- Cyclosporine, clarithromycin, HIV protease inhibitors, itraconazole – avoid co-use with cyclosporine; others raise risk.
- Digoxin – monitor levels.
- Oral contraceptives – consider increased levels of norethindrone and ethinyl estradiol.
- Colchicine – caution advised.
- Warfarin – monitor INR when initiating or discontinuing Taven EZ.
✔️ Storage ConditionContraindications
- Active liver disease or persistently elevated liver enzymes.
- Known hypersensitivity to any of the product’s components.
✔️ Pregnancy & Lactation
Pregnancy Category X: Contraindicated during pregnancy due to potential harm to the fetus and lack of benefit.
Breastfeeding is also not recommended, as small amounts of statins may pass into breast milk.
✔️ Storage
- Store below 30°C.
- Keep in a cool, dry location away from direct light.
- Ensure the medicine is out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
